SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2msk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 7 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.92A 11gsA-2mskA:
undetectable		 11gsA-2mskA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 8 PHE A 106
ASP A  10
LEU A  52
LEU A  23
 None
 0.99A 2bfpA-2mskA:
3.6		 2bfpA-2mskA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 8 PHE A 106
ASP A  10
LEU A  52
LEU A  23
 None
 0.95A 2bfpB-2mskA:
undetectable		 2bfpB-2mskA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		5 / 11 ALA A 113
ALA A  24
GLY A  25
ALA A  22
ASP A 109
 None
 1.17A 2f16H-2mskA:
undetectable
2f16I-2mskA:
undetectable		 2f16H-2mskA:
21.24
2f16I-2mskA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		5 / 11 ALA A 113
ALA A  24
GLY A  25
ALA A  22
ASP A 109
 None
 1.17A 2f16V-2mskA:
undetectable
2f16W-2mskA:
undetectable		 2f16V-2mskA:
21.24
2f16W-2mskA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 7 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.90A 3gssA-2mskA:
undetectable		 3gssA-2mskA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 7 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.90A 3gssB-2mskA:
undetectable		 3gssB-2mskA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 8 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.95A 3hjoA-2mskA:
undetectable		 3hjoA-2mskA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		5 / 12 GLY A  62
GLY A  36
ASN A  37
ILE A  80
LEU A  66
 None
 0.98A 3ihtA-2mskA:
undetectable		 3ihtA-2mskA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 8 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.94A 3n9jA-2mskA:
undetectable		 3n9jA-2mskA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 5 LYS A  70
VAL A  50
ILE A  69
ARG A 117
 None
 1.45A 3pyyB-2mskA:
undetectable		 3pyyB-2mskA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 2msk NITROGEN REGULATION
PROTEIN NR(I)
(Salmonella
enterica) 		4 / 7 ALA A  89
GLY A  97
ALA A  98
SER A  53
 None
 0.78A 4r1zB-2mskA:
undetectable		 4r1zB-2mskA:
13.93