SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2msr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 2msr PC4 AND
SFRS1-INTERACTING
PROTEIN
(Homo
sapiens) 		3 / 3 GLU B 379
GLN B 353
ARG B 344
 None
 0.94A 2w3bB-2msrB:
undetectable		 2w3bB-2msrB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2msr PC4 AND
SFRS1-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 8 SER B 347
GLU B 345
MET B 387
VAL B 385
THR B 386
 None
 1.27A 4lnwA-2msrB:
undetectable		 4lnwA-2msrB:
16.03