SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2msv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 LEU A  42
PRO A  41
LEU A  45
 None
 0.61A 2po5B-2msvA:
undetectable		 2po5B-2msvA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		4 / 7 TYR A  23
LEU A  97
LEU A  89
SER A  83
 None
 1.01A 3lm8A-2msvA:
undetectable
3lm8C-2msvA:
undetectable		 3lm8A-2msvA:
20.18
3lm8C-2msvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		4 / 8 TYR A  23
LEU A  97
LEU A  89
SER A  83
 None
 1.01A 3lm8B-2msvA:
undetectable
3lm8D-2msvA:
undetectable		 3lm8B-2msvA:
20.18
3lm8D-2msvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		4 / 7 ILE A   7
LEU A   4
LEU A  45
SER A 125
 None
 0.96A 3r9vA-2msvA:
undetectable
3r9vB-2msvA:
undetectable		 3r9vA-2msvA:
19.86
3r9vB-2msvA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 ASN A 102
ALA A 134
LYS A  99
 None
 0.97A 3runA-2msvA:
undetectable		 3runA-2msvA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		5 / 11 LEU A  69
LEU A  10
ILE A   7
LEU A  38
ILE A  76
 None
 1.19A 4dm8A-2msvA:
undetectable		 4dm8A-2msvA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 GLY A  32
LEU A  36
HIS A  15
 None
 0.62A 5u63A-2msvA:
undetectable		 5u63A-2msvA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 2msv MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 GLY A  32
LEU A  36
HIS A  15
 None
 0.58A 5u63B-2msvA:
undetectable		 5u63B-2msvA:
21.78