SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2msx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 2msx KUNITZ-TYPE PROTEASE
INHIBITOR 1
(Homo
sapiens) 		3 / 3 VAL A 102
ALA A 114
PHE A 117
 None
 0.80A 4olbA-2msxA:
undetectable		 4olbA-2msxA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 2msx KUNITZ-TYPE PROTEASE
INHIBITOR 1
(Homo
sapiens) 		3 / 3 VAL A 102
ALA A 114
PHE A 117
 None
 0.82A 4w5nA-2msxA:
undetectable		 4w5nA-2msxA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2msx KUNITZ-TYPE PROTEASE
INHIBITOR 1
(Homo
sapiens) 		3 / 3 VAL A 102
ALA A 114
PHE A 117
 None
 0.83A 4z4iA-2msxA:
undetectable		 4z4iA-2msxA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2msx KUNITZ-TYPE PROTEASE
INHIBITOR 1
(Homo
sapiens) 		3 / 3 VAL A 102
ALA A 114
PHE A 117
 None
 0.80A 5js1A-2msxA:
undetectable		 5js1A-2msxA:
9.69