SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mt4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JAY_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	2mt4	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Bacillus subtilis)	5 / 12	GLU A 4 VAL A 118 ASP A 7 ILE A 11 GLU A 15	None	1.20A	3jayA-2mt4A: undetectable	3jayA-2mt4A: 8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB3_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	2mt4	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Bacillus subtilis)	5 / 12	GLU A 4 VAL A 118 ASP A 7 ILE A 11 GLU A 15	None	1.23A	3jb3A-2mt4A: 2.0	3jb3A-2mt4A: 8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB6_A_ADNA401_1 (ADENOSINE KINASE)	2mt4	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Bacillus subtilis)	5 / 12	GLY A 54 ILE A 27 ALA A 106 GLY A 103 ALA A 107	None	0.91A	5kb6A-2mt4A: undetectable	5kb6A-2mt4A: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB6_B_ADNB401_1 (ADENOSINE KINASE)	2mt4	TRANSCRIPTION TERMINATION/ANTITERM INATION PROTEIN NUSA (Bacillus subtilis)	5 / 12	GLY A 54 ILE A 27 ALA A 106 GLY A 103 ALA A 107	None	0.93A	5kb6B-2mt4A: undetectable	5kb6B-2mt4A: 20.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3JAY_A_SAMA1101_0","STRUCTURAL PROTEIN VP3","2mt4","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Bacillus subtilis",5,"GLU A   4;VAL A 118;ASP A   7;ILE A  11;GLU A  15","None","1.20A","3jayA-2mt4A:undetectable","3jayA-2mt4A:8.41"],["3JB3_A_SAMA1101_0","STRUCTURAL PROTEIN VP3","2mt4","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Bacillus subtilis",5,"GLU A   4;VAL A 118;ASP A   7;ILE A  11;GLU A  15","None","1.23A","3jb3A-2mt4A:2.0","3jb3A-2mt4A:8.41"],["5KB6_A_ADNA401_1","ADENOSINE KINASE","2mt4","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Bacillus subtilis",5,"GLY A  54;ILE A  27;ALA A 106;GLY A 103;ALA A 107","None","0.91A","5kb6A-2mt4A:undetectable","5kb6A-2mt4A:20.37"],["5KB6_B_ADNB401_1","ADENOSINE KINASE","2mt4","TRANSCRIPTION TERMINATION\/ANTITERMINATION PROTEIN NUSA","Bacillus subtilis",5,"GLY A  54;ILE A  27;ALA A 106;GLY A 103;ALA A 107","None","0.93A","5kb6B-2mt4A:undetectable","5kb6B-2mt4A:20.37"]]