SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		5 / 7 THR A  11
THR A  55
TRP A  56
GLY A  88
TYR A  93
 FMN  A 201 (-2.8A)
FMN  A 201 (-3.9A)
FMN  A 201 (-3.5A)
FMN  A 201 (-3.1A)
FMN  A 201 (-3.5A)
 1.13A 1bu5A-2mt9A:
20.3		 1bu5A-2mt9A:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		4 / 7 THR A  55
GLY A  88
ASP A  89
TYR A  93
 FMN  A 201 (-3.9A)
FMN  A 201 (-3.1A)
None
FMN  A 201 (-3.5A)
 0.66A 1bu5A-2mt9A:
20.3		 1bu5A-2mt9A:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		4 / 8 THR A  55
GLY A  88
ASP A  89
TYR A  93
 FMN  A 201 (-3.9A)
FMN  A 201 (-3.1A)
None
FMN  A 201 (-3.5A)
 0.70A 1bu5B-2mt9A:
20.4		 1bu5B-2mt9A:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		3 / 3 VAL A 140
TRP A 119
TRP A 160
 None
 1.01A 1c4dA-2mt9A:
undetectable
1c4dB-2mt9A:
undetectable		 1c4dA-2mt9A:
8.77
1c4dB-2mt9A:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		5 / 8 ALA A  17
GLY A  86
ILE A  53
ILE A  50
ILE A  21
 None
 1.15A 1hshD-2mt9A:
undetectable		 1hshD-2mt9A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		3 / 3 SER A  39
ASP A  64
ASP A  37
 None
 0.74A 2plwA-2mt9A:
undetectable		 2plwA-2mt9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		5 / 10 ILE A  61
TRP A  69
SER A 128
VAL A 132
VAL A 140
 None
 1.46A 3burA-2mt9A:
undetectable		 3burA-2mt9A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		4 / 5 LEU A  98
ARG A 156
LEU A 101
PRO A 131
 None
 1.34A 3onnA-2mt9A:
undetectable		 3onnA-2mt9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		4 / 6 ASP A  38
LEU A  35
ALA A  18
LEU A  32
 None
 1.12A 3rozA-2mt9A:
3.5		 3rozA-2mt9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2mt9 FLAVODOXIN-2
(Escherichia
coli) 		4 / 8 GLY A  94
ASP A  89
ASP A 145
THR A 121
 None
 0.71A 4eyrB-2mt9A:
undetectable		 4eyrB-2mt9A:
21.18