SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mta'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 2mta METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)
(Paracoccus
denitrificans) 		4 / 7 TYR L 119
ASN L 104
GLY L  93
TRP L  13
 None
TRQ  L  57 ( 4.8A)
None
None
 1.27A 1mxgA-2mtaL:
undetectable		 1mxgA-2mtaL:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 2mta METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)
(Paracoccus
denitrificans) 		3 / 3 TRP L  13
VAL L  14
PRO L  15
 None
 0.37A 1rg1A-2mtaL:
undetectable		 1rg1A-2mtaL:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 2mta METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)
(Paracoccus
denitrificans) 		3 / 3 TRP L  13
VAL L  14
PRO L  15
 None
 0.37A 1rh0A-2mtaL:
undetectable		 1rh0A-2mtaL:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 2mta METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)
(Paracoccus
denitrificans) 		4 / 6 THR L  44
ASN L  45
GLY L  41
ASP L  37
 None
 1.24A 3w9tE-2mtaL:
undetectable		 3w9tE-2mtaL:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 2mta CYTOCHROME C551I
(Paracoccus
denitrificans) 		4 / 5 LEU C 108
ASP C 111
ARG C 115
ILE C  45
 None
 1.11A 4mwrA-2mtaC:
undetectable		 4mwrA-2mtaC:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 2mta METHYLAMINE
DEHYDROGENASE (LIGHT
SUBUNIT)
(Paracoccus
denitrificans) 		4 / 8 ILE L 107
GLY L  33
THR L 122
LEU L  89
 None
None
TRQ  L  57 ( 3.1A)
None
 0.96A 5hwaA-2mtaL:
undetectable		 5hwaA-2mtaL:
18.68