SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mtc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 2mtc DECORIN-BINDING
PROTEIN A
(Borreliella
burgdorferi) 		5 / 10 ALA A  92
PHE A  95
ALA A  42
LEU A  38
LEU A 129
 None
 1.03A 2bxqA-2mtcA:
undetectable		 2bxqA-2mtcA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 2mtc DECORIN-BINDING
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 ILE A  99
PHE A  95
ALA A 103
THR A 109
LEU A  38
 None
 1.16A 3s79A-2mtcA:
undetectable		 3s79A-2mtcA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BCS_A_ACTA1126_0
(CHIMERIC AVIDIN)		 2mtc DECORIN-BINDING
PROTEIN A
(Borreliella
burgdorferi) 		4 / 4 THR A 172
GLN A 168
ARG A 169
THR A 165
 None
 1.25A 4bcsA-2mtcA:
undetectable		 4bcsA-2mtcA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 2mtc DECORIN-BINDING
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 ILE A  99
PHE A  95
ALA A 103
THR A 109
LEU A  38
 None
 1.18A 5jkvA-2mtcA:
undetectable		 5jkvA-2mtcA:
15.76