SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mtg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 2mtg LA-RELATED PROTEIN 6
(Homo
sapiens) 		3 / 3 ASP A 190
LEU A 197
LEU A 191
 None
 0.69A 1ikeA-2mtgA:
undetectable		 1ikeA-2mtgA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2mtg LA-RELATED PROTEIN 6
(Homo
sapiens) 		4 / 7 VAL A 230
ILE A 232
VAL A 188
ALA A 259
 None
 0.67A 5ospA-2mtgA:
undetectable		 5ospA-2mtgA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2mtg LA-RELATED PROTEIN 6
(Homo
sapiens) 		4 / 7 VAL A 230
ILE A 232
VAL A 188
ALA A 259
 None
 0.69A 5osrA-2mtgA:
undetectable		 5osrA-2mtgA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2mtg LA-RELATED PROTEIN 6
(Homo
sapiens) 		4 / 9 VAL A 213
HIS A 216
LEU A 187
ASP A 190
 None
 0.90A 6c2mD-2mtgA:
undetectable		 6c2mD-2mtgA:
20.00