SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mu3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 11 LEU A 117
ALA A  13
VAL A 120
LEU A  94
GLN A  42
 None
 1.31A 1kt7A-2mu3A:
undetectable		 1kt7A-2mu3A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		4 / 7 ALA A  67
GLY A 134
ASP A 132
ASP A  62
 None
 0.81A 2uyqA-2mu3A:
undetectable		 2uyqA-2mu3A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 12 PHE A  95
PHE A  90
ASN A 104
GLY A 109
LEU A  17
 None
 1.26A 3aobC-2mu3A:
undetectable		 3aobC-2mu3A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 12 ILE A 105
LEU A 117
GLY A  98
ALA A  97
VAL A 120
 None
 0.92A 3rukB-2mu3A:
undetectable		 3rukB-2mu3A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 9 ALA A   9
GLY A  11
LEU A 117
ASN A 104
ILE A 105
 None
 1.38A 3wdmA-2mu3A:
undetectable		 3wdmA-2mu3A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 9 ALA A   9
LEU A 117
LEU A 108
ASN A 104
ILE A 105
 None
 1.18A 3wdmA-2mu3A:
undetectable		 3wdmA-2mu3A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 9 ALA A   9
LEU A 117
LEU A 108
ASN A 104
ILE A 105
 None
 1.18A 3wdmC-2mu3A:
undetectable		 3wdmC-2mu3A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 12 PRO A   3
GLY A   6
GLY A   5
GLY A 109
LEU A 117
 None
 1.08A 4fp9F-2mu3A:
undetectable		 4fp9F-2mu3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		5 / 12 PRO A   3
GLY A   6
GLY A   5
GLY A 109
LEU A 117
 None
 1.08A 4fzvA-2mu3A:
undetectable		 4fzvA-2mu3A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 2mu3 ACINIFORM SPIDROIN 1
(Argiope
trifasciata) 		4 / 5 GLY A 178
LEU A  25
SER A 151
GLN A 158
 None
 1.35A 6ji6A-2mu3A:
undetectable		 6ji6A-2mu3A:
20.08