SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2muo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 2muo SECRETED
LY-6/UPAR-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 SER A 153
ASP A 125
MET A 129
ILE A 169
ARG A 149
 None
 1.20A 1s14A-2muoA:
undetectable		 1s14A-2muoA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 2muo SECRETED
LY-6/UPAR-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 SER A 153
ASP A 125
MET A 129
ILE A 169
ARG A 149
 None
 1.24A 3lpsA-2muoA:
undetectable		 3lpsA-2muoA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 2muo SECRETED
LY-6/UPAR-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 153
ASP A 125
MET A 129
ILE A 169
ARG A 149
 None
 1.41A 4urnA-2muoA:
undetectable		 4urnA-2muoA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 2muo SECRETED
LY-6/UPAR-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 153
ASP A 125
MET A 129
ILE A 169
ARG A 149
 None
 1.30A 4urnB-2muoA:
undetectable		 4urnB-2muoA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 2muo SECRETED
LY-6/UPAR-RELATED
PROTEIN 1
(Homo
sapiens) 		5 / 11 SER A 153
ASP A 125
MET A 129
ILE A 169
ARG A 149
 None
 1.27A 4urnC-2muoA:
undetectable		 4urnC-2muoA:
14.22