SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2mux UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		4 / 5 LEU A  36
ASP A  32
ALA A  39
ILE A  35
 None
 1.05A 2aofB-2muxA:
undetectable		 2aofB-2muxA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2mux UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		3 / 3 ASP A  98
LYS A  99
ASP A 101
 None
 0.80A 4a7tA-2muxA:
undetectable		 4a7tA-2muxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2mux UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		4 / 7 GLY A  29
THR A  28
ILE A  27
PHE A  20
 None
 0.94A 4acaC-2muxA:
undetectable		 4acaC-2muxA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 2mux UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		5 / 11 GLY A  45
LEU A  49
PHE A  20
ALA A  39
PHE A  53
 None
 1.44A 6qgbA-2muxA:
undetectable		 6qgbA-2muxA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 2mux UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		5 / 11 GLY A  45
LEU A  49
PHE A  20
ALA A  39
PHE A  53
 None
 1.45A 6qgbE-2muxA:
undetectable		 6qgbE-2muxA:
14.62