SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2muy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 2muy ATP-DEPENDENT ZINC
METALLOPROTEASE FTSH
(Escherichia
coli) 		3 / 3 GLU A  95
HIS A 100
HIS A 103
 None
 0.69A 3co4A-2muyA:
undetectable		 3co4A-2muyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 2muy ATP-DEPENDENT ZINC
METALLOPROTEASE FTSH
(Escherichia
coli) 		4 / 5 ILE A  56
THR A  68
THR A  67
PHE A  37
 None
 1.07A 3snfA-2muyA:
undetectable		 3snfA-2muyA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2muy ATP-DEPENDENT ZINC
METALLOPROTEASE FTSH
(Escherichia
coli) 		4 / 4 VAL A  88
ILE A  56
ASN A  80
VAL A  46
 None
 1.31A 5ajqA-2muyA:
undetectable		 5ajqA-2muyA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 2muy ATP-DEPENDENT ZINC
METALLOPROTEASE FTSH
(Escherichia
coli) 		3 / 3 ARG A  47
LYS A  87
GLU A  48
 None
 0.69A 5d0yA-2muyA:
undetectable		 5d0yA-2muyA:
18.39