SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RG7_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	2mvo	PUTATIVE LIPOPROTEIN (Microbispora sp. ATCC PTA-5024)	5 / 12	ASN A 66 LEU A 52 THR A 79 ILE A 80 LEU A 137	None	1.01A	1rg7A-2mvoA: undetectable	1rg7A-2mvoA: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	2mvo	PUTATIVE LIPOPROTEIN (Microbispora sp. ATCC PTA-5024)	5 / 12	SER A 54 ASP A 61 ILE A 80 THR A 79 LEU A 137	None	1.27A	3iv6A-2mvoA: undetectable	3iv6A-2mvoA: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D1Y_A_RBFA1176_1 (PUTATIVE PROTEASE I)	2mvo	PUTATIVE LIPOPROTEIN (Microbispora sp. ATCC PTA-5024)	4 / 8	ASN A 66 GLN A 60 ASN A 136 THR A 134	None	1.44A	4d1yA-2mvoA: undetectable 4d1yB-2mvoA: undetectable	4d1yA-2mvoA: 22.51 4d1yB-2mvoA: 22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H5F_A_SAMA301_1 (PROTEIN ARGININE N-METHYLTRANSFERASE SFM1)	2mvo	PUTATIVE LIPOPROTEIN (Microbispora sp. ATCC PTA-5024)	4 / 5	PRO A 53 THR A 79 GLN A 60 THR A 134	None	1.30A	5h5fA-2mvoA: undetectable	5h5fA-2mvoA: 22.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RG7_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","2mvo","PUTATIVE LIPOPROTEIN","Microbispora sp. ATCC PTA-5024",5,"ASN A  66;LEU A  52;THR A  79;ILE A  80;LEU A 137","None","1.01A","1rg7A-2mvoA:undetectable","1rg7A-2mvoA:20.61"],["3IV6_A_SAMA301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","2mvo","PUTATIVE LIPOPROTEIN","Microbispora sp. ATCC PTA-5024",5,"SER A  54;ASP A  61;ILE A  80;THR A  79;LEU A 137","None","1.27A","3iv6A-2mvoA:undetectable","3iv6A-2mvoA:21.37"],["4D1Y_A_RBFA1176_1","PUTATIVE PROTEASE I;PUTATIVE PROTEASE I","2mvo","PUTATIVE LIPOPROTEIN","Microbispora sp. ATCC PTA-5024",4,"ASN A  66;GLN A  60;ASN A 136;THR A 134","None","1.44A","4d1yA-2mvoA:undetectable;4d1yB-2mvoA:undetectable","4d1yA-2mvoA:22.51;4d1yB-2mvoA:22.51"],["5H5F_A_SAMA301_1","PROTEIN ARGININE N-METHYLTRANSFERASE SFM1","2mvo","PUTATIVE LIPOPROTEIN","Microbispora sp. ATCC PTA-5024",4,"PRO A  53;THR A  79;GLN A  60;THR A 134","None","1.30A","5h5fA-2mvoA:undetectable","5h5fA-2mvoA:22.97"]]