SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mvz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		4 / 8 ILE A   7
PHE A  31
GLY A  56
GLY A  57
 None
 0.56A 2qx4A-2mvzA:
undetectable
2qx4B-2mvzA:
undetectable		 2qx4A-2mvzA:
21.74
2qx4B-2mvzA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		4 / 6 ILE A   7
PHE A  31
GLY A  56
GLY A  57
 None
 0.61A 2qx6A-2mvzA:
undetectable
2qx6B-2mvzA:
undetectable		 2qx6A-2mvzA:
21.74
2qx6B-2mvzA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		6 / 12 THR A  64
ALA A  90
GLY A  97
THR A  70
LEU A 111
PHE A 102
 None
 1.34A 2y7hB-2mvzA:
undetectable		 2y7hB-2mvzA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_0
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		6 / 12 THR A  64
ALA A  90
GLY A  97
THR A  70
LEU A 111
PHE A 102
 None
 1.34A 2y7hC-2mvzA:
undetectable		 2y7hC-2mvzA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		4 / 8 ILE A   7
THR A  27
LEU A  19
VAL A 142
 None
 0.87A 3ua5A-2mvzA:
undetectable		 3ua5A-2mvzA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		3 / 3 LEU A  43
GLY A  56
PHE A 118
 None
 0.67A 6exiC-2mvzA:
undetectable		 6exiC-2mvzA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 2mvz PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Geobacillus
kaustophilus) 		3 / 3 LYS A   3
VAL A 142
ASP A 144
 None
 0.50A 6fgdA-2mvzA:
undetectable		 6fgdA-2mvzA:
16.11