SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 VAL A  28
ASN A  37
ASN A 104
LEU A 106
ILE A 108
GLN A 123
 None
FMN  A 900 ( 4.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 ( 4.1A)
FMN  A 900 (-4.2A)
 0.77A 4kukA-2mwgA:
14.8		 4kukA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 VAL A  28
ASN A  61
CYH A  62
ASN A 104
LEU A 106
ILE A 108
 None
FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 ( 4.1A)
 1.27A 4kukA-2mwgA:
14.8		 4kukA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		9 / 12 VAL A  28
ASN A  61
CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
ILE A 108
GLN A 123
 None
FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 ( 4.1A)
FMN  A 900 (-4.2A)
 0.85A 4kukA-2mwgA:
14.8		 4kukA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 VAL A  28
CYH A  62
ARG A  63
ASN A  94
ASN A 104
GLN A 123
 None
FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.2A)
 1.18A 4kukA-2mwgA:
14.8		 4kukA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 9 LEU A  65
ILE A  78
ARG A  79
LEU A  82
ILE A  92
GLY A 121
 FMN  A 900 ( 4.1A)
FMN  A 900 ( 4.7A)
None
FMN  A 900 ( 4.8A)
FMN  A 900 ( 4.1A)
FMN  A 900 (-2.9A)
 1.17A 4kukA-2mwgA:
14.8		 4kukA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 9 LEU A  65
VAL A  75
ILE A  78
LEU A  82
ILE A  92
PHE A 119
GLY A 121
 FMN  A 900 ( 4.1A)
None
FMN  A 900 ( 4.7A)
FMN  A 900 ( 4.8A)
FMN  A 900 ( 4.1A)
None
FMN  A 900 (-2.9A)
 0.78A 4kukA-2mwgA:
14.8		 4kukA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 ASN A  61
GLN A  66
LEU A  82
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 FMN  A 900 (-2.0A)
FMN  A 900 (-2.6A)
FMN  A 900 ( 4.8A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.87A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		5 / 12 VAL A  28
ASN A  37
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 900 ( 4.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.60A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		5 / 12 VAL A  28
ASN A  61
CYH A  62
ASN A 104
LEU A 106
 None
FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
 1.38A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		8 / 12 VAL A  28
ASN A  61
CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.79A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 VAL A  28
CYH A  62
ARG A  63
ASN A  94
ASN A 104
GLN A 123
 None
FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.2A)
 1.19A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 CYH A  62
ARG A  63
ASN A  94
ASN A 104
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 1.23A 4r38A-2mwgA:
6.5		 4r38A-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 0.60A 4r38A-2mwgA:
6.5		 4r38A-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		4 / 8 ASN A  61
LEU A  65
VAL A  75
ILE A  92
 FMN  A 900 (-2.0A)
FMN  A 900 ( 4.1A)
None
FMN  A 900 ( 4.1A)
 0.47A 4r38A-2mwgA:
6.5		 4r38A-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 ASN A  61
CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.71A 4r38B-2mwgA:
15.3		 4r38B-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 CYH A  62
ARG A  63
ASN A  94
ASN A 104
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 1.24A 4r38B-2mwgA:
15.3		 4r38B-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 0.56A 4r38B-2mwgA:
15.3		 4r38B-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 0.62A 4r38C-2mwgA:
15.3		 4r38C-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 0.64A 4r38D-2mwgA:
15.1		 4r38D-2mwgA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		6 / 12 CYH A  62
ARG A  63
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 1.17A 4r3aA-2mwgA:
12.2		 4r3aA-2mwgA:
29.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
GLN A  66
ILE A  92
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 ( 4.1A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.57A 4r3aA-2mwgA:
12.2		 4r3aA-2mwgA:
29.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		5 / 8 ASN A  61
LEU A  65
VAL A  75
PHE A 119
GLY A 121
 FMN  A 900 (-2.0A)
FMN  A 900 ( 4.1A)
None
None
FMN  A 900 (-2.9A)
 1.06A 4r3aA-2mwgA:
12.2		 4r3aA-2mwgA:
29.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		5 / 10 ASN A  61
LEU A  65
GLN A  66
VAL A  75
PHE A 119
 FMN  A 900 (-2.0A)
FMN  A 900 ( 4.1A)
FMN  A 900 (-2.6A)
None
None
 1.14A 4r3aB-2mwgA:
12.5		 4r3aB-2mwgA:
29.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
ARG A  63
ASN A  94
ASN A 104
LEU A 106
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 1.09A 4r3aB-2mwgA:
12.5		 4r3aB-2mwgA:
29.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2mwg BLUE-LIGHT
PHOTORECEPTOR
(Bacillus
subtilis) 		7 / 12 CYH A  62
ILE A  92
ASN A  94
ASN A 104
LEU A 106
GLY A 121
GLN A 123
 FMN  A 900 (-3.3A)
FMN  A 900 ( 4.1A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-2.9A)
FMN  A 900 (-4.2A)
 0.60A 4r3aB-2mwgA:
12.5		 4r3aB-2mwgA:
29.94