SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mwh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2mwh ANTI-HIV LECTIN OAA
(Planktothrix
agardhii) 		5 / 8 LEU A  92
VAL A   6
LEU A 114
VAL A  33
VAL A  38
 None
 1.33A 2bdmA-2mwhA:
undetectable		 2bdmA-2mwhA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 2mwh ANTI-HIV LECTIN OAA
(Planktothrix
agardhii) 		4 / 8 ALA A  35
SER A 107
GLY A 111
ALA A  54
 None
 0.88A 2vh3B-2mwhA:
undetectable		 2vh3B-2mwhA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 2mwh ANTI-HIV LECTIN OAA
(Planktothrix
agardhii) 		4 / 5 LEU A 114
GLY A 130
MET A 118
ASN A   8
 None
 0.89A 3uq6B-2mwhA:
undetectable		 3uq6B-2mwhA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2mwh ANTI-HIV LECTIN OAA
(Planktothrix
agardhii) 		3 / 3 GLN A  45
THR A  46
THR A  64
 None
 0.75A 4fu9A-2mwhA:
undetectable		 4fu9A-2mwhA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2mwh ANTI-HIV LECTIN OAA
(Planktothrix
agardhii) 		3 / 3 GLN A  45
THR A  46
THR A  64
 None
 0.74A 4fufA-2mwhA:
undetectable		 4fufA-2mwhA:
22.13