SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mx9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_A_SAMA500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2mx9	MINOR AMPULLATE SPIDROIN (Araneus ventricosus)	5 / 11	THR A 105 ALA A 111 GLU A 115 ALA A 71 PRO A 7	None	1.17A	2admA-2mx9A: undetectable	2admA-2mx9A: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ADM_B_SAMB500_0 (ADENINE-N6-DNA-METHY LTRANSFERASE TAQI)	2mx9	MINOR AMPULLATE SPIDROIN (Araneus ventricosus)	5 / 11	THR A 105 ALA A 111 GLU A 115 ALA A 71 PRO A 7	None	1.18A	2admB-2mx9A: undetectable	2admB-2mx9A: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_B_CELB1701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	2mx9	MINOR AMPULLATE SPIDROIN (Araneus ventricosus)	4 / 6	LEU A 22 ILE A 8 ALA A 71 LEU A 119	None	0.89A	3kk6B-2mx9A: undetectable	3kk6B-2mx9A: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XT7_A_TOPA302_1 (RV2671)	2mx9	MINOR AMPULLATE SPIDROIN (Araneus ventricosus)	5 / 11	ASN A 67 ILE A 8 THR A 17 ASP A 109 PHE A 112	None	1.19A	4xt7A-2mx9A: undetectable	4xt7A-2mx9A: 20.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ADM_A_SAMA500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2mx9","MINOR AMPULLATE SPIDROIN","Araneus ventricosus",5,"THR A 105;ALA A 111;GLU A 115;ALA A  71;PRO A   7","None","1.17A","2admA-2mx9A:undetectable","2admA-2mx9A:14.29"],["2ADM_B_SAMB500_0","ADENINE-N6-DNA-METHYLTRANSFERASE TAQI","2mx9","MINOR AMPULLATE SPIDROIN","Araneus ventricosus",5,"THR A 105;ALA A 111;GLU A 115;ALA A  71;PRO A   7","None","1.18A","2admB-2mx9A:undetectable","2admB-2mx9A:14.29"],["3KK6_B_CELB1701_2","PROSTAGLANDIN G\/H SYNTHASE 1","2mx9","MINOR AMPULLATE SPIDROIN","Araneus ventricosus",4,"LEU A  22;ILE A   8;ALA A  71;LEU A 119","None","0.89A","3kk6B-2mx9A:undetectable","3kk6B-2mx9A:13.62"],["4XT7_A_TOPA302_1","RV2671","2mx9","MINOR AMPULLATE SPIDROIN","Araneus ventricosus",5,"ASN A  67;ILE A   8;THR A  17;ASP A 109;PHE A 112","None","1.19A","4xt7A-2mx9A:undetectable","4xt7A-2mx9A:20.54"]]