SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mxa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2mxa NDH-1 COMPLEX
SENSORY SUBUNIT CUPS
(Thermosynechococ
cus
elongatus) 		5 / 11 ILE A 123
ALA A 114
ALA A 113
ASN A  42
ALA A  79
 None
 1.12A 2aclE-2mxaA:
undetectable		 2aclE-2mxaA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 2mxa NDH-1 COMPLEX
SENSORY SUBUNIT CUPS
(Thermosynechococ
cus
elongatus) 		5 / 12 ILE A 116
PRO A  41
ILE A  96
VAL A 106
VAL A 111
 None
 1.25A 3iw1A-2mxaA:
undetectable		 3iw1A-2mxaA:
17.65