SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mxp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZI9_A_CL9A401_2 (DEOXYCYTIDINE KINASE)	2mxp	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	3 / 3	ASP A 74 PHE A 77 LEU A 81	None	0.66A	2zi9A-2mxpA: undetectable	2zi9A-2mxpA: 10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_A_CUA601_0 (LACCASE-1)	2mxp	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 5	HIS A 75 CYH A 57 ILE A 59 HIS A 79	ZN A 101 (-3.2A) ZN A 101 (-2.3A) ZN A 101 ( 4.3A) ZN A 101 (-3.1A)	1.41A	3qpkA-2mxpA: undetectable	3qpkA-2mxpA: 4.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_B_CUB601_0 (LACCASE-1)	2mxp	CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2 (Homo sapiens)	4 / 4	HIS A 75 CYH A 57 ILE A 59 HIS A 79	ZN A 101 (-3.2A) ZN A 101 (-2.3A) ZN A 101 ( 4.3A) ZN A 101 (-3.1A)	1.39A	3qpkB-2mxpA: undetectable	3qpkB-2mxpA: 4.94