SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2my7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2my7 CUGBP ELAV-LIKE
FAMILY MEMBER 2
(Homo
sapiens) 		5 / 9 ASP A 420
ILE A 421
GLY A 417
GLY A 449
ARG A 482
 None
 1.32A 4acaB-2my7A:
undetectable
4acaC-2my7A:
undetectable		 4acaB-2my7A:
11.60
4acaC-2my7A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2my7 CUGBP ELAV-LIKE
FAMILY MEMBER 2
(Homo
sapiens) 		4 / 4 LYS A 484
ASP A 439
ASN A 443
SER A 487
 None
 1.46A 4obwB-2my7A:
undetectable		 4obwB-2my7A:
20.75