SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5V_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.09A	3n5vA-2mz8A: undetectable 3n5vB-2mz8A: undetectable	3n5vA-2mz8A: 16.31 3n5vB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N5Y_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.06A	3n5yA-2mz8A: undetectable 3n5yB-2mz8A: undetectable	3n5yA-2mz8A: 16.31 3n5yB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JSF_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.07A	4jsfA-2mz8A: undetectable 4jsfB-2mz8A: undetectable	4jsfA-2mz8A: 16.31 4jsfB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AD4_A_H4BA760_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.07A	5ad4A-2mz8A: undetectable 5ad4B-2mz8A: undetectable	5ad4A-2mz8A: 16.31 5ad4B-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNT_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.08A	5untA-2mz8A: undetectable 5untB-2mz8A: undetectable	5untA-2mz8A: 16.31 5untB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNU_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.14A	5unuA-2mz8A: undetectable 5unuB-2mz8A: undetectable	5unuA-2mz8A: 16.31 5unuB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNV_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 6	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.04A	5unvA-2mz8A: undetectable 5unvB-2mz8A: undetectable	5unvA-2mz8A: 16.31 5unvB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNV_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 6	GLU A 89 ARG A 51 VAL A 40 TRP A 54	None	1.10A	5unvA-2mz8A: undetectable 5unvB-2mz8A: undetectable	5unvA-2mz8A: 16.31 5unvB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNY_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.12A	5unyA-2mz8A: undetectable 5unyB-2mz8A: undetectable	5unyA-2mz8A: 16.31 5unyB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UNZ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	GLU A 89 ARG A 51 VAL A 40 TRP A 54	None	1.13A	5unzA-2mz8A: undetectable 5unzB-2mz8A: undetectable	5unzA-2mz8A: 16.31 5unzB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UO3_B_H4BB803_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	GLU A 89 ARG A 51 VAL A 40 TRP A 54	None	1.12A	5uo3A-2mz8A: undetectable 5uo3B-2mz8A: undetectable	5uo3A-2mz8A: 15.33 5uo3B-2mz8A: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUJ_A_H4BA802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	ARG A 51 VAL A 40 TRP A 54 GLU A 89	None	1.12A	5vujA-2mz8A: undetectable 5vujB-2mz8A: undetectable	5vujA-2mz8A: 16.31 5vujB-2mz8A: 16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VUJ_B_H4BB802_1 (NITRIC OXIDE SYNTHASE, BRAIN)	2mz8	SIGMA FACTOR-BINDING PROTEIN CRL (Salmonella enterica)	4 / 7	GLU A 89 ARG A 51 VAL A 40 TRP A 54	None	1.11A	5vujA-2mz8A: undetectable 5vujB-2mz8A: undetectable	5vujA-2mz8A: 16.31 5vujB-2mz8A: 16.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3N5V_A_H4BA760_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.09A","3n5vA-2mz8A:undetectable;3n5vB-2mz8A:undetectable","3n5vA-2mz8A:16.31;3n5vB-2mz8A:16.31"],["3N5Y_A_H4BA760_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.06A","3n5yA-2mz8A:undetectable;3n5yB-2mz8A:undetectable","3n5yA-2mz8A:16.31;3n5yB-2mz8A:16.31"],["4JSF_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.07A","4jsfA-2mz8A:undetectable;4jsfB-2mz8A:undetectable","4jsfA-2mz8A:16.31;4jsfB-2mz8A:16.31"],["5AD4_A_H4BA760_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.07A","5ad4A-2mz8A:undetectable;5ad4B-2mz8A:undetectable","5ad4A-2mz8A:16.31;5ad4B-2mz8A:16.31"],["5UNT_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.08A","5untA-2mz8A:undetectable;5untB-2mz8A:undetectable","5untA-2mz8A:16.31;5untB-2mz8A:16.31"],["5UNU_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.14A","5unuA-2mz8A:undetectable;5unuB-2mz8A:undetectable","5unuA-2mz8A:16.31;5unuB-2mz8A:16.31"],["5UNV_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.04A","5unvA-2mz8A:undetectable;5unvB-2mz8A:undetectable","5unvA-2mz8A:16.31;5unvB-2mz8A:16.31"],["5UNV_B_H4BB802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"GLU A  89;ARG A  51;VAL A  40;TRP A  54","None","1.10A","5unvA-2mz8A:undetectable;5unvB-2mz8A:undetectable","5unvA-2mz8A:16.31;5unvB-2mz8A:16.31"],["5UNY_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.12A","5unyA-2mz8A:undetectable;5unyB-2mz8A:undetectable","5unyA-2mz8A:16.31;5unyB-2mz8A:16.31"],["5UNZ_B_H4BB802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"GLU A  89;ARG A  51;VAL A  40;TRP A  54","None","1.13A","5unzA-2mz8A:undetectable;5unzB-2mz8A:undetectable","5unzA-2mz8A:16.31;5unzB-2mz8A:16.31"],["5UO3_B_H4BB803_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"GLU A  89;ARG A  51;VAL A  40;TRP A  54","None","1.12A","5uo3A-2mz8A:undetectable;5uo3B-2mz8A:undetectable","5uo3A-2mz8A:15.33;5uo3B-2mz8A:15.33"],["5VUJ_A_H4BA802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"ARG A  51;VAL A  40;TRP A  54;GLU A  89","None","1.12A","5vujA-2mz8A:undetectable;5vujB-2mz8A:undetectable","5vujA-2mz8A:16.31;5vujB-2mz8A:16.31"],["5VUJ_B_H4BB802_1","NITRIC OXIDE SYNTHASE, BRAIN;NITRIC OXIDE SYNTHASE, BRAIN","2mz8","SIGMA FACTOR-BINDING PROTEIN CRL","Salmonella enterica",4,"GLU A  89;ARG A  51;VAL A  40;TRP A  54","None","1.11A","5vujA-2mz8A:undetectable;5vujB-2mz8A:undetectable","5vujA-2mz8A:16.31;5vujB-2mz8A:16.31"]]