SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mzr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 2mzr PROTEIN HRB1
(Saccharomyces
cerevisiae) 		4 / 5 SER A 162
LEU A 177
GLY A 203
GLU A 206
 None
 1.13A 3aiaA-2mzrA:
undetectable
3aiaB-2mzrA:
undetectable		 3aiaA-2mzrA:
17.48
3aiaB-2mzrA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2mzr PROTEIN HRB1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 230
ALA A 216
VAL A 205
VAL A 165
 None
 0.65A 3me6B-2mzrA:
undetectable		 3me6B-2mzrA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2mzr PROTEIN HRB1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 196
HIS A 198
ARG A 200
 None
 1.14A 6dwdD-2mzrA:
undetectable		 6dwdD-2mzrA:
9.96