SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2n1g DNA REPAIR PROTEIN
REV1
(Homo
sapiens) 		4 / 8 LEU A1248
ILE A1210
LEU A1206
LEU A1240
 None
 0.80A 2xfhA-2n1gA:
undetectable		 2xfhA-2n1gA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 2n1g DNA REPAIR PROTEIN
REV1
(Homo
sapiens) 		3 / 3 LEU A1208
ASP A1196
ILE A1198
 None
 0.61A 6dh0B-2n1gA:
undetectable		 6dh0B-2n1gA:
20.59