SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIV_A_T3A933_1
(ANDROGEN RECEPTOR)		 2n1i PR DOMAIN ZINC
FINGER PROTEIN 16
(Homo
sapiens) 		5 / 9 ILE A 188
GLY A 127
GLU A 129
GLU A 190
ARG A 118
 None
 1.35A 2pivA-2n1iA:
undetectable		 2pivA-2n1iA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2n1i PR DOMAIN ZINC
FINGER PROTEIN 16
(Homo
sapiens) 		5 / 11 SER A 167
ALA A 165
ILE A  78
LEU A  86
ILE A 172
 None
 1.19A 4xumB-2n1iA:
undetectable		 4xumB-2n1iA:
21.82