SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n1k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2n1k FIBRONECTIN
(Homo
sapiens) 		3 / 3 ARG A  29
SER A  88
TYR A  80
 None
 0.67A 1x70A-2n1kA:
undetectable		 1x70A-2n1kA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2n1k FIBRONECTIN
(Homo
sapiens) 		3 / 3 LEU A  57
PRO A  58
ARG A  29
 None
 0.64A 2qd5A-2n1kA:
undetectable		 2qd5A-2n1kA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2n1k FIBRONECTIN
(Homo
sapiens) 		3 / 3 GLN A  94
THR A  78
ASN A  76
 None
 0.89A 3v4tE-2n1kA:
undetectable		 3v4tE-2n1kA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2n1k FIBRONECTIN
(Homo
sapiens) 		4 / 6 ILE A  93
ARG A  29
THR A  65
LEU A  66
 None
 1.01A 5zcoN-2n1kA:
undetectable
5zcoW-2n1kA:
undetectable		 5zcoN-2n1kA:
11.71
5zcoW-2n1kA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2n1k FIBRONECTIN
(Homo
sapiens) 		4 / 7 ILE A  93
ARG A  29
THR A  65
LEU A  66
 None
 0.93A 5zcpA-2n1kA:
undetectable
5zcpJ-2n1kA:
undetectable		 5zcpA-2n1kA:
11.71
5zcpJ-2n1kA:
17.92