SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n2e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 2n2e NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		3 / 3 ARG A 161
SER A 170
TYR A 195
 None
 0.90A 2q2hA-2n2eA:
undetectable
2q2hB-2n2eA:
undetectable		 2q2hA-2n2eA:
25.85
2q2hB-2n2eA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2n2e NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		4 / 4 GLY A 196
GLU A 197
ASP A 155
ASP A 194
 None
 1.19A 3mb5A-2n2eA:
undetectable		 3mb5A-2n2eA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2n2e NISIN IMMUNITY
PROTEIN
(Lactococcus
lactis) 		3 / 3 ASP A 182
LYS A 181
ASP A 180
 None
 0.72A 4a7tA-2n2eA:
undetectable		 4a7tA-2n2eA:
22.01