SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n2l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 2n2l OUTER MEMBRANE
PROTEIN X
(Yersinia
pestis) 		3 / 3 ASN A  30
TYR A  88
SER A   7
 None
 0.70A 2gvcB-2n2lA:
undetectable		 2gvcB-2n2lA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 2n2l OUTER MEMBRANE
PROTEIN X
(Yersinia
pestis) 		3 / 3 ASN A  30
TYR A  88
SER A   7
 None
 0.71A 2gvcE-2n2lA:
undetectable		 2gvcE-2n2lA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 2n2l OUTER MEMBRANE
PROTEIN X
(Yersinia
pestis) 		5 / 12 TYR A  88
GLY A 153
ILE A   6
ILE A 131
ALA A 152
 None
 1.13A 4qtuD-2n2lA:
undetectable		 4qtuD-2n2lA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 2n2l OUTER MEMBRANE
PROTEIN X
(Yersinia
pestis) 		4 / 8 ASN A  25
PRO A  26
TRP A 148
TYR A 137
 None
 1.42A 5oh1C-2n2lA:
undetectable		 5oh1C-2n2lA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 2n2l OUTER MEMBRANE
PROTEIN X
(Yersinia
pestis) 		3 / 3 SER A 114
SER A 138
ALA A  48
 None
 0.72A 6dwnC-2n2lA:
undetectable		 6dwnC-2n2lA:
19.25