SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n3f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
2n3f DOUBLE-STRANDED
RNA-BINDING PROTEIN
4

(Arabidopsis
thaliana)
5 / 12 GLY A  44
CYH A  43
TYR A  12
LEU A  71
HIS A  16
None
1.41A 1zgyA-2n3fA:
undetectable
1zgyA-2n3fA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2n3f DOUBLE-STRANDED
RNA-BINDING PROTEIN
4

(Arabidopsis
thaliana)
4 / 7 LYS A   6
LEU A   9
GLN A  10
PHE A  47
None
1.04A 2eijP-2n3fA:
undetectable
2eijW-2n3fA:
undetectable
2eijP-2n3fA:
20.58
2eijW-2n3fA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)
2n3f DOUBLE-STRANDED
RNA-BINDING PROTEIN
4

(Arabidopsis
thaliana)
3 / 3 LEU A  86
VAL A  81
ASP A  80
None
0.45A 4y8wC-2n3fA:
undetectable
4y8wC-2n3fA:
16.84