SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2n3o POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LYS A  65
TYR A 127
ARG A  64
 G  B   9 ( 2.7A)
G  B   9 ( 4.9A)
G  B   9 ( 3.1A)
 0.88A 4gc9A-2n3oA:
undetectable		 4gc9A-2n3oA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2n3o POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1
(Homo
sapiens) 		6 / 12 GLU A 135
ALA A 106
ALA A 107
MET A 110
VAL A 111
THR A  86
 None
 1.02A 5igjA-2n3oA:
1.1		 5igjA-2n3oA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2n3o POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 8 VAL A  60
HIS A 133
PRO A  57
GLY A  49
 None
U  B  12 ( 2.8A)
None
None
 0.83A 5w3jB-2n3oA:
undetectable		 5w3jB-2n3oA:
13.68