SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 PHE A  88
LEU A  36
GLU A  38
LEU A  64
 None
 0.90A 1eupA-2n47A:
undetectable		 1eupA-2n47A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 ALA A  37
GLY A  39
ASP A  58
LEU A  85
 None
 0.39A 2uyqA-2n47A:
9.2		 2uyqA-2n47A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLY A  39
ASP A  58
SER A  60
 None
 0.70A 3brfA-2n47A:
undetectable		 3brfA-2n47A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ALA A  37
GLY A  39
SER A  60
PHE A 102
LEU A 109
 None
 0.88A 3bxoA-2n47A:
12.4		 3bxoA-2n47A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 CYH A 103
HIS A 104
PHE A 102
 None
 1.23A 3cr4X-2n47A:
undetectable		 3cr4X-2n47A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 5 PHE A 132
PHE A 102
LEU A 150
PRO A 144
 None
 1.03A 4o8zA-2n47A:
4.6		 4o8zA-2n47A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 187
ALA A 186
LEU A 175
GLY A 142
LEU A 147
 None
 1.07A 4xi3C-2n47A:
undetectable		 4xi3C-2n47A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 ALA A  56
VAL A  57
ASP A  58
GLY A  97
SER A 100
 None
 1.22A 4xnxA-2n47A:
undetectable		 4xnxA-2n47A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2n47 SLR1183 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 ALA A  37
GLY A  39
GLY A  41
ASN A  84
 None
 0.48A 5ybbB-2n47A:
7.8		 5ybbB-2n47A:
16.17