SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n4i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 2n4i SELECTION AND UPKEEP
OF INTRAEPITHELIAL
T-CELLS PROTEIN 1
(Mus
musculus) 		4 / 8 ARG A  77
LEU A  75
PRO A  53
GLY A 128
 None
 0.98A 1hrkB-2n4iA:
undetectable		 1hrkB-2n4iA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2n4i SELECTION AND UPKEEP
OF INTRAEPITHELIAL
T-CELLS PROTEIN 1
(Mus
musculus) 		3 / 3 GLY A 128
GLU A  61
ASP A 129
 None
 0.61A 2b25B-2n4iA:
undetectable		 2b25B-2n4iA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 2n4i SELECTION AND UPKEEP
OF INTRAEPITHELIAL
T-CELLS PROTEIN 1
(Mus
musculus) 		3 / 3 HIS A 134
GLU A 133
HIS A 122
 None
 0.82A 3ba0A-2n4iA:
undetectable		 3ba0A-2n4iA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2n4i SELECTION AND UPKEEP
OF INTRAEPITHELIAL
T-CELLS PROTEIN 1
(Mus
musculus) 		3 / 3 GLN A  50
GLU A 103
LYS A 105
 None
 1.03A 3su9A-2n4iA:
undetectable		 3su9A-2n4iA:
13.54