SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n4x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2n4x CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
(CCDA)
(Archaeoglobus
fulgidus) 		4 / 6 ALA A 123
TYR A 142
ILE A 125
ILE A 127
 None
 1.16A 2dcfA-2n4xA:
undetectable		 2dcfA-2n4xA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2n4x CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
(CCDA)
(Archaeoglobus
fulgidus) 		4 / 7 ALA A 123
TYR A 142
ILE A 125
ILE A 127
 None
 1.15A 2zm7A-2n4xA:
undetectable		 2zm7A-2n4xA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2n4x CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
(CCDA)
(Archaeoglobus
fulgidus) 		5 / 9 ALA A 123
TYR A 142
ILE A 125
GLY A 124
ILE A 127
 None
 1.10A 2zm9A-2n4xA:
0.0		 2zm9A-2n4xA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2n4x CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
(CCDA)
(Archaeoglobus
fulgidus) 		4 / 8 ALA A 123
TYR A 142
GLY A 124
ILE A 127
 None
 0.91A 2zm9A-2n4xA:
undetectable		 2zm9A-2n4xA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2n4x CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
(CCDA)
(Archaeoglobus
fulgidus) 		5 / 11 ALA A 118
GLY A 173
ALA A 174
THR A 149
VAL A 153
 None
 1.15A 3rukD-2n4xA:
undetectable		 3rukD-2n4xA:
20.65