SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 8 THR A  40
VAL A  41
LEU A  38
ALA A  35
 None
 0.95A 1fiqC-2n57A:
undetectable		 1fiqC-2n57A:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 6 THR A  40
VAL A  41
LEU A  38
ALA A  35
 None
 0.97A 2e1qA-2n57A:
undetectable		 2e1qA-2n57A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 6 THR A  40
VAL A  41
LEU A  38
ALA A  35
 None
 1.01A 2e1qC-2n57A:
undetectable		 2e1qC-2n57A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 8 THR A  40
VAL A  41
LEU A  38
ALA A  35
 None
 0.97A 3ax7A-2n57A:
undetectable		 3ax7A-2n57A:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 8 ASP A  57
SER A  37
PHE A  72
LEU A  43
 None
 0.90A 3m0wE-2n57A:
undetectable
3m0wF-2n57A:
2.1
3m0wG-2n57A:
2.1
3m0wH-2n57A:
undetectable		 3m0wE-2n57A:
20.59
3m0wF-2n57A:
20.59
3m0wG-2n57A:
20.59
3m0wH-2n57A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 7 THR A  40
VAL A  41
LEU A  38
ALA A  35
 None
 1.01A 3uniA-2n57A:
undetectable		 3uniA-2n57A:
4.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		4 / 8 ALA A  59
ASP A  57
VAL A  53
ILE A  55
 None
 0.68A 4ll3A-2n57A:
undetectable		 4ll3A-2n57A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		5 / 12 ILE A  63
VAL A   8
VAL A  12
ALA A  59
VAL A  41
 None
 1.11A 5n0oA-2n57A:
undetectable		 5n0oA-2n57A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		5 / 12 ILE A  63
VAL A   8
VAL A  12
ALA A  59
VAL A  41
 None
 1.13A 5n0rA-2n57A:
undetectable		 5n0rA-2n57A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		5 / 12 ILE A  63
VAL A   8
VAL A  12
ALA A  59
VAL A  41
 None
 1.09A 5n0sA-2n57A:
undetectable		 5n0sA-2n57A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		5 / 12 ILE A  63
VAL A   8
VAL A  12
ALA A  59
VAL A  41
 None
 1.11A 5n0sB-2n57A:
undetectable		 5n0sB-2n57A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2n57 ACYL CARRIER PROTEIN
(Brucella
melitensis) 		5 / 12 ILE A  63
VAL A   8
VAL A  12
ALA A  59
VAL A  41
 None
 1.14A 5n0wA-2n57A:
undetectable		 5n0wA-2n57A:
14.29