SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2n7d PROTEIN DDI1 HOMOLOG
2
(Homo
sapiens) 		3 / 3 SER A 163
ASP A 124
ASP A 156
 None
 0.85A 3iv6A-2n7dA:
undetectable		 3iv6A-2n7dA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 2n7d PROTEIN DDI1 HOMOLOG
2
(Homo
sapiens) 		3 / 3 SER A 163
ASP A 124
ASP A 156
 None
 0.77A 3iv6C-2n7dA:
undetectable		 3iv6C-2n7dA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 2n7d PROTEIN DDI1 HOMOLOG
2
(Homo
sapiens) 		4 / 5 ALA A 162
HIS A 100
MET A 101
ARG A  99
 None
 1.36A 4ac9B-2n7dA:
undetectable
4ac9C-2n7dA:
undetectable		 4ac9B-2n7dA:
12.76
4ac9C-2n7dA:
12.76