SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z2B_C_VLBC800_1 (TUBULIN BETA CHAIN TUBULIN ALPHA CHAIN)	2n7g	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2 (Homo sapiens)	4 / 8	VAL A 60 TYR A 70 THR A 67 LEU A 152	None	0.93A	1z2bB-2n7gA: undetectable	1z2bB-2n7gA: 16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1161_1 (ALLERGEN ARG R 1)	2n7g	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2 (Homo sapiens)	4 / 5	TYR A 70 VAL A 60 ASP A 64 SER A 108	None	1.35A	2x45C-2n7gA: undetectable	2x45C-2n7gA: 19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_A_V2HA602_1 (CYTOCHROME P450 2R1)	2n7g	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2 (Homo sapiens)	4 / 5	ASN A 151 ALA A 68 LEU A 65 GLY A 106	None	0.94A	3dl9A-2n7gA: undetectable	3dl9A-2n7gA: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JJK_A_FOLA601_0 (FORMATE--TETRAHYDROF OLATE LIGASE)	2n7g	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2 (Homo sapiens)	4 / 8	ALA A 114 LEU A 120 TYR A 70 LEU A 59	None	0.96A	4jjkA-2n7gA: undetectable	4jjkA-2n7gA: 14.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Z2B_C_VLBC800_1","TUBULIN BETA CHAIN;TUBULIN ALPHA CHAIN","2n7g","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2","Homo sapiens",4,"VAL A  60;TYR A  70;THR A  67;LEU A 152","None","0.93A","1z2bB-2n7gA:undetectable","1z2bB-2n7gA:16.11"],["2X45_C_HSMC1161_1","ALLERGEN ARG R 1","2n7g","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2","Homo sapiens",4,"TYR A  70;VAL A  60;ASP A  64;SER A 108","None","1.35A","2x45C-2n7gA:undetectable","2x45C-2n7gA:19.32"],["3DL9_A_V2HA602_1","CYTOCHROME P450 2R1","2n7g","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2","Homo sapiens",4,"ASN A 151;ALA A  68;LEU A  65;GLY A 106","None","0.94A","3dl9A-2n7gA:undetectable","3dl9A-2n7gA:15.66"],["4JJK_A_FOLA601_0","FORMATE--TETRAHYDROFOLATE LIGASE","2n7g","POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2","Homo sapiens",4,"ALA A 114;LEU A 120;TYR A  70;LEU A  59","None","0.96A","4jjkA-2n7gA:undetectable","4jjkA-2n7gA:14.78"]]