SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_4 (POL POLYPROTEIN)	2n7p	PUTATIVE UNCHARACTERIZED PROTEIN (Trypanosoma brucei)	3 / 3	ARG A 90 VAL A 28 GLY A 43	None	0.48A	2avvE-2n7pA: undetectable	2avvE-2n7pA: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D20_A_017A201_1 (HIV-1 PROTEASE)	2n7p	PUTATIVE UNCHARACTERIZED PROTEIN (Trypanosoma brucei)	5 / 12	GLY A 49 ALA A 48 VAL A 101 ILE A 25 ILE A 99	None	1.09A	3d20A-2n7pA: undetectable	3d20A-2n7pA: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MWS_B_017B201_1 (HIV-1 PROTEASE)	2n7p	PUTATIVE UNCHARACTERIZED PROTEIN (Trypanosoma brucei)	5 / 12	GLY A 49 ALA A 48 VAL A 101 ILE A 25 ILE A 99	None	1.06A	3mwsA-2n7pA: undetectable	3mwsA-2n7pA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2n7p	PUTATIVE UNCHARACTERIZED PROTEIN (Trypanosoma brucei)	4 / 5	ILE A 25 PHE A 9 ARG A 58 THR A 65	None	1.28A	5z84N-2n7pA: undetectable 5z84W-2n7pA: undetectable	5z84N-2n7pA: 10.70 5z84W-2n7pA: 17.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AVV_E_MK1E902_4","POL POLYPROTEIN","2n7p","PUTATIVE UNCHARACTERIZED PROTEIN","Trypanosoma brucei",3,"ARG A  90;VAL A  28;GLY A  43","None","0.48A","2avvE-2n7pA:undetectable","2avvE-2n7pA:20.91"],["3D20_A_017A201_1","HIV-1 PROTEASE","2n7p","PUTATIVE UNCHARACTERIZED PROTEIN","Trypanosoma brucei",5,"GLY A  49;ALA A  48;VAL A 101;ILE A  25;ILE A  99","None","1.09A","3d20A-2n7pA:undetectable","3d20A-2n7pA:20.91"],["3MWS_B_017B201_1","HIV-1 PROTEASE;HIV-1 PROTEASE","2n7p","PUTATIVE UNCHARACTERIZED PROTEIN","Trypanosoma brucei",5,"GLY A  49;ALA A  48;VAL A 101;ILE A  25;ILE A  99","None","1.06A","3mwsA-2n7pA:undetectable","3mwsA-2n7pA:20.72"],["5Z84_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2n7p","PUTATIVE UNCHARACTERIZED PROTEIN","Trypanosoma brucei",4,"ILE A  25;PHE A   9;ARG A  58;THR A  65","None","1.28A","5z84N-2n7pA:undetectable;5z84W-2n7pA:undetectable","5z84N-2n7pA:10.70;5z84W-2n7pA:17.92"]]