SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	2n82	RNA BINDING PROTEIN FOX-1 HOMOLOG 1 (Homo sapiens)	4 / 6	PHE B 163 ILE B 143 ARG B 134 VAL B 121	None	1.36A	4mk4B-2n82B: undetectable	4mk4B-2n82B: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTA_H_MFXH101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA)	2n82	RNA BINDING PROTEIN FOX-1 HOMOLOG 1 (Homo sapiens)	4 / 6	SER B 122 ARG B 153 GLY B 154 GLU B 152	A A 31 ( 3.0A) C A 30 ( 3.6A) U A 26 ( 3.1A) U A 27 ( 3.1A)	1.05A	5btaA-2n82B: 2.6 5btaB-2n82B: undetectable 5btaC-2n82B: 2.6	5btaA-2n82B: 12.13 5btaB-2n82B: 17.39 5btaC-2n82B: 12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTC_G_CPFG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	2n82	RNA BINDING PROTEIN FOX-1 HOMOLOG 1 (Homo sapiens)	4 / 6	SER B 122 ARG B 153 GLY B 154 GLU B 152	A A 31 ( 3.0A) C A 30 ( 3.6A) U A 26 ( 3.1A) U A 27 ( 3.1A)	1.01A	5btcA-2n82B: 2.6 5btcC-2n82B: 2.5 5btcD-2n82B: undetectable	5btcA-2n82B: 12.13 5btcC-2n82B: 12.13 5btcD-2n82B: 17.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4MK4_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","2n82","RNA BINDING PROTEIN FOX-1 HOMOLOG 1","Homo sapiens",4,"PHE B 163;ILE B 143;ARG B 134;VAL B 121","None","1.36A","4mk4B-2n82B:undetectable","4mk4B-2n82B:14.90"],["5BTA_H_MFXH101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","2n82","RNA BINDING PROTEIN FOX-1 HOMOLOG 1","Homo sapiens",4,"SER B 122;ARG B 153;GLY B 154;GLU B 152","  A A  31 ( 3.0A);  C A  30 ( 3.6A);  U A  26 ( 3.1A);  U A  27 ( 3.1A)","1.05A","5btaA-2n82B:2.6;5btaB-2n82B:undetectable;5btaC-2n82B:2.6","5btaA-2n82B:12.13;5btaB-2n82B:17.39;5btaC-2n82B:12.13"],["5BTC_G_CPFG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","2n82","RNA BINDING PROTEIN FOX-1 HOMOLOG 1","Homo sapiens",4,"SER B 122;ARG B 153;GLY B 154;GLU B 152","  A A  31 ( 3.0A);  C A  30 ( 3.6A);  U A  26 ( 3.1A);  U A  27 ( 3.1A)","1.01A","5btcA-2n82B:2.6;5btcC-2n82B:2.5;5btcD-2n82B:undetectable","5btcA-2n82B:12.13;5btcC-2n82B:12.13;5btcD-2n82B:17.39"]]