SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)
2n84 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei)
5 / 12 LEU A  87
ALA A 152
SER A 156
CYH A  71
PHE A 119
None
1.19A 4udaA-2n84A:
undetectable
4udaA-2n84A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
2n84 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei)
4 / 4 LEU A 139
GLY A 141
SER A 157
SER A 156
None
1.05A 5uunA-2n84A:
undetectable
5uunA-2n84A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
2n84 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei)
4 / 4 LEU A 139
GLY A 141
SER A 157
SER A 156
None
1.14A 5uunB-2n84A:
undetectable
5uunB-2n84A:
20.76