SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n8f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		3 / 3 ALA A  73
VAL A  43
TRP A  45
 None
 0.90A 1bdwA-2n8fA:
undetectable
1bdwB-2n8fA:
undetectable		 1bdwA-2n8fA:
15.38
1bdwB-2n8fA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD6_0
(GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		4 / 5 TRP A  45
TRP A  62
ALA A  73
VAL A  43
 None
 1.41A 2xdcC-2n8fA:
undetectable
2xdcD-2n8fA:
undetectable		 2xdcC-2n8fA:
15.38
2xdcD-2n8fA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF6_0
(GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		4 / 5 TRP A  45
TRP A  62
ALA A  73
VAL A  43
 None
 1.41A 2xdcE-2n8fA:
undetectable
2xdcF-2n8fA:
undetectable		 2xdcE-2n8fA:
15.38
2xdcF-2n8fA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_D_DVAD6_0
(VAL-GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		4 / 5 TRP A  45
TRP A  62
ALA A  73
VAL A  43
 None
 1.41A 2y5mC-2n8fA:
undetectable
2y5mD-2n8fA:
undetectable		 2y5mC-2n8fA:
15.38
2y5mD-2n8fA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF6_0
(VAL-GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		4 / 5 TRP A  45
TRP A  62
ALA A  73
VAL A  43
 None
 1.41A 2y5mE-2n8fA:
undetectable
2y5mF-2n8fA:
undetectable		 2y5mE-2n8fA:
15.38
2y5mF-2n8fA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD6_0
(VAL-GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		4 / 5 TRP A  45
TRP A  62
ALA A  73
VAL A  43
 None
 1.40A 2y6nC-2n8fA:
undetectable
2y6nD-2n8fA:
undetectable		 2y6nC-2n8fA:
15.38
2y6nD-2n8fA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF6_0
(VAL-GRAMICIDIN A)		 2n8f SPIDER TOXIN
PI-HEXATOXIN-HI1A
(Hadronyche
infensa) 		4 / 5 TRP A  45
TRP A  62
ALA A  73
VAL A  43
 None
 1.41A 2y6nE-2n8fA:
undetectable
2y6nF-2n8fA:
undetectable		 2y6nE-2n8fA:
15.38
2y6nF-2n8fA:
15.38