SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		4 / 7 VAL A  53
THR A  54
THR A  68
ARG A  66
 None
 1.17A 2kotA-2n8nA:
undetectable		 2kotA-2n8nA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 1.00A 2pynB-2n8nA:
undetectable		 2pynB-2n8nA:
25.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 1.00A 2qakB-2n8nA:
undetectable		 2qakB-2n8nA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 1.11A 3nu5B-2n8nA:
undetectable		 3nu5B-2n8nA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 1.03A 3oxxA-2n8nA:
undetectable		 3oxxA-2n8nA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 1.02A 3tkgD-2n8nA:
undetectable		 3tkgD-2n8nA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 1.03A 4jecB-2n8nA:
undetectable		 4jecB-2n8nA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		3 / 3 LYS A  39
ILE A  40
ILE A  47
 None
 0.73A 4y0qA-2n8nA:
undetectable		 4y0qA-2n8nA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		5 / 12 LEU A  26
GLY A  65
ALA A  34
VAL A  13
ILE A  47
 None
 0.98A 6dh6A-2n8nA:
undetectable		 6dh6A-2n8nA:
28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 2n8n TRANSLATION
INITIATION FACTOR
IF-1
(Staphylococcus
aureus) 		3 / 3 VAL A  53
GLU A  10
ILE A  67
 None
 0.56A 6f7lB-2n8nA:
undetectable		 6f7lB-2n8nA:
12.53