SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n8x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 2n8x LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Pseudomonas
aeruginosa) 		5 / 11 THR A  48
VAL A 119
ASN A  98
GLU A  76
ASP A 147
 None
 1.10A 1t6zA-2n8xA:
undetectable		 1t6zA-2n8xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2n8x LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A  70
ILE A 104
LEU A  34
 None
 0.71A 2kceA-2n8xA:
undetectable		 2kceA-2n8xA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2n8x LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 147
ASP A  77
ASN A 101
GLN A 118
 None
 1.16A 5l6eA-2n8xA:
undetectable		 5l6eA-2n8xA:
21.94