SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2n9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 2n9u RESPONSE REGULATOR
(Erythrobacter
litoralis) 		5 / 9 LEU A 257
GLY A 166
VAL A 249
ILE A 169
ILE A 253
 None
 0.99A 1hpvA-2n9uA:
undetectable		 1hpvA-2n9uA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2n9u RESPONSE REGULATOR
(Erythrobacter
litoralis) 		5 / 8 GLY A 171
ALA A 170
ASP A 168
LEU A 192
VAL A 216
 None
 1.33A 3em6A-2n9uA:
undetectable		 3em6A-2n9uA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2n9u RESPONSE REGULATOR
(Erythrobacter
litoralis) 		5 / 12 LEU A 192
LEU A 158
LEU A 161
ILE A 253
ILE A 221
 None
 1.11A 4a7aB-2n9uA:
undetectable		 4a7aB-2n9uA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 2n9u RESPONSE REGULATOR
(Erythrobacter
litoralis) 		4 / 6 ALA A 206
ALA A 173
LEU A 197
THR A 175
 None
 1.05A 4dtzB-2n9uA:
undetectable		 4dtzB-2n9uA:
13.88