SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2na0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2na0 GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Bos
taurus) 		4 / 7 VAL A 160
LEU A 167
THR A 171
LEU A 174
 None
 0.79A 1jgsA-2na0A:
undetectable		 1jgsA-2na0A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 2na0 GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Bos
taurus) 		4 / 7 TYR A  99
PHE A  65
ILE A 119
LEU A 174
 None
 1.00A 4uymB-2na0A:
undetectable		 4uymB-2na0A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2na0 GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Bos
taurus) 		4 / 7 THR A 169
LEU A 170
THR A 136
LEU A 112
 None
 0.92A 4z91F-2na0A:
undetectable
4z91G-2na0A:
undetectable
4z91H-2na0A:
undetectable
4z91I-2na0A:
undetectable
4z91J-2na0A:
undetectable		 4z91F-2na0A:
20.06
4z91G-2na0A:
20.06
4z91H-2na0A:
20.06
4z91I-2na0A:
20.06
4z91J-2na0A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 2na0 GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Bos
taurus) 		4 / 8 LEU A 166
LEU A 170
LEU A 113
ARG A 117
 None
 0.92A 6ce2A-2na0A:
undetectable		 6ce2A-2na0A:
17.22