SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2na1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2na1 POLYCOMB COMPLEX
PROTEIN BMI-1,
POLYHOMEOTIC-LIKE 2
(Homo
sapiens;
Mus
musculus) 		4 / 5 LEU A 223
LEU A 175
LEU A 164
SER A 132
 None
 1.00A 3vhuA-2na1A:
undetectable		 3vhuA-2na1A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 2na1 POLYCOMB COMPLEX
PROTEIN BMI-1,
POLYHOMEOTIC-LIKE 2
(Homo
sapiens;
Mus
musculus) 		4 / 8 ARG A 165
GLU A  48
GLY A 219
PRO A 220
 None
 0.99A 5kf8A-2na1A:
undetectable		 5kf8A-2na1A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 2na1 POLYCOMB COMPLEX
PROTEIN BMI-1,
POLYHOMEOTIC-LIKE 2
(Homo
sapiens;
Mus
musculus) 		4 / 8 ARG A 165
GLU A  48
GLY A 219
PRO A 220
 None
 1.01A 5kgpA-2na1A:
undetectable		 5kgpA-2na1A:
17.92