SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2naz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 2naz TRANSCRIPTIONAL
REGULATORY PROTEIN
RSTA
(Acinetobacter
baumannii) 		4 / 6 ALA A 163
ASP A 166
GLU A 164
ARG A 206
 None
 1.21A 2ouzA-2nazA:
undetectable		 2ouzA-2nazA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 2naz TRANSCRIPTIONAL
REGULATORY PROTEIN
RSTA
(Acinetobacter
baumannii) 		5 / 9 ILE A 221
ILE A 211
LYS A 210
GLU A 164
LEU A 167
 None
 1.15A 3f78A-2nazA:
undetectable		 3f78A-2nazA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2naz TRANSCRIPTIONAL
REGULATORY PROTEIN
RSTA
(Acinetobacter
baumannii) 		4 / 5 TYR A 193
ARG A 189
GLU A 164
VAL A 158
 None
 1.35A 4nkvB-2nazA:
undetectable		 4nkvB-2nazA:
13.56