SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 2nbg TRANSLATION
INITIATION FACTOR
IF-2
(Geobacillus
stearothermophil
us) 		5 / 12 ALA A 441
PHE A 494
GLY A 453
THR A 454
THR A 455
 None
 1.13A 2zifA-2nbgA:
undetectable		 2zifA-2nbgA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 2nbg TRANSLATION
INITIATION FACTOR
IF-2
(Geobacillus
stearothermophil
us) 		4 / 6 GLY A 447
MET A 400
ILE A 450
VAL A 459
 None
 1.17A 3kvvA-2nbgA:
undetectable		 3kvvA-2nbgA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 2nbg TRANSLATION
INITIATION FACTOR
IF-2
(Geobacillus
stearothermophil
us) 		4 / 6 GLY A 447
MET A 400
ILE A 450
VAL A 459
 None
 1.15A 3kvvC-2nbgA:
undetectable		 3kvvC-2nbgA:
21.83