SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 2nbi HEP200 PROTEIN
(Cylindrotheca
fusiformis) 		4 / 4 ARG A 516
ASP A 522
ASP A 519
PRO A 518
 None
 1.37A 3fgrB-2nbiA:
undetectable		 3fgrB-2nbiA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 2nbi HEP200 PROTEIN
(Cylindrotheca
fusiformis) 		4 / 5 TYR A 117
PRO A 169
THR A 174
THR A 151
 None
 1.45A 3q07A-2nbiA:
undetectable		 3q07A-2nbiA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 2nbi HEP200 PROTEIN
(Cylindrotheca
fusiformis) 		4 / 5 TYR A 117
PRO A 169
THR A 174
THR A 151
 None
 1.44A 3q07B-2nbiA:
undetectable		 3q07B-2nbiA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 2nbi HEP200 PROTEIN
(Cylindrotheca
fusiformis) 		5 / 9 ALA A 283
PRO A 284
GLN A 287
GLY A 308
SER A 311
 None
 1.28A 4a3uA-2nbiA:
undetectable		 4a3uA-2nbiA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 2nbi HEP200 PROTEIN
(Cylindrotheca
fusiformis) 		3 / 3 SER A 125
TYR A 117
ASP A 156
 None
 0.89A 4rp8C-2nbiA:
undetectable		 4rp8C-2nbiA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 2nbi HEP200 PROTEIN
(Cylindrotheca
fusiformis) 		3 / 3 TYR A 307
ASP A 309
ASP A 357
 None
 0.85A 5x6yA-2nbiA:
undetectable		 5x6yA-2nbiA:
19.14