SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nda'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_C_ADNC1503_1 (CLASS B ACID PHOSPHATASE)	2nda	MID-CELL-ANCHORED PROTEIN Z (Streptococcus pneumoniae)	4 / 8	TYR A 113 LEU A 111 GLY A 104 ASP A 109	None	1.03A	1rmtC-2ndaA: undetectable	1rmtC-2ndaA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	2nda	MID-CELL-ANCHORED PROTEIN Z (Streptococcus pneumoniae)	4 / 8	MET A 10 ARG A 21 VAL A 17 GLY A 16	None	1.15A	2qd3A-2ndaA: undetectable	2qd3A-2ndaA: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I45_A_NIOA500_1 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN)	2nda	MID-CELL-ANCHORED PROTEIN Z (Streptococcus pneumoniae)	4 / 8	PHE A 91 LEU A 68 TYR A 66 LEU A 48	None	0.90A	3i45A-2ndaA: undetectable	3i45A-2ndaA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID6_C_SAMC301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	2nda	MID-CELL-ANCHORED PROTEIN Z (Streptococcus pneumoniae)	5 / 12	TYR A 79 GLY A 78 SER A 39 ASP A 35 ALA A 32	None	1.19A	3id6C-2ndaA: undetectable	3id6C-2ndaA: 21.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RMT_C_ADNC1503_1","CLASS B ACID PHOSPHATASE","2nda","MID-CELL-ANCHORED PROTEIN Z","Streptococcus pneumoniae",4,"TYR A 113;LEU A 111;GLY A 104;ASP A 109","None","1.03A","1rmtC-2ndaA:undetectable","1rmtC-2ndaA:20.18"],["2QD3_A_CHDA502_0","FERROCHELATASE","2nda","MID-CELL-ANCHORED PROTEIN Z","Streptococcus pneumoniae",4,"MET A  10;ARG A  21;VAL A  17;GLY A  16","None","1.15A","2qd3A-2ndaA:undetectable","2qd3A-2ndaA:14.69"],["3I45_A_NIOA500_1","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN","2nda","MID-CELL-ANCHORED PROTEIN Z","Streptococcus pneumoniae",4,"PHE A  91;LEU A  68;TYR A  66;LEU A  48","None","0.90A","3i45A-2ndaA:undetectable","3i45A-2ndaA:15.67"],["3ID6_C_SAMC301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","2nda","MID-CELL-ANCHORED PROTEIN Z","Streptococcus pneumoniae",5,"TYR A  79;GLY A  78;SER A  39;ASP A  35;ALA A  32","None","1.19A","3id6C-2ndaA:undetectable","3id6C-2ndaA:21.26"]]