SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2nlv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2nlv XISI PROTEIN-LIKE
(Trichormus
variabilis) 		3 / 3 ILE A  63
ILE A  68
THR A  36
 None
 0.59A 1rg7A-2nlvA:
undetectable		 1rg7A-2nlvA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2nlv XISI PROTEIN-LIKE
(Trichormus
variabilis) 		4 / 6 ASP A  62
TYR A   7
TYR A  41
LEU A   4
 None
 1.19A 2w98A-2nlvA:
undetectable
2w98B-2nlvA:
undetectable		 2w98A-2nlvA:
14.24
2w98B-2nlvA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 2nlv XISI PROTEIN-LIKE
(Trichormus
variabilis) 		4 / 6 LEU A  83
LYS A   6
GLN A   8
LEU A  10
 None
 1.08A 3h5gB-2nlvA:
undetectable
3h5gC-2nlvA:
undetectable		 3h5gB-2nlvA:
10.81
3h5gC-2nlvA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2nlv XISI PROTEIN-LIKE
(Trichormus
variabilis) 		3 / 3 ASP A  22
SER A  24
ARG A  56
 None
 1.02A 3loqA-2nlvA:
undetectable		 3loqA-2nlvA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2nlv XISI PROTEIN-LIKE
(Trichormus
variabilis) 		4 / 8 GLY A  87
TYR A  18
LEU A  14
TYR A   7
 None
 0.76A 4fgzA-2nlvA:
undetectable		 4fgzA-2nlvA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 2nlv XISI PROTEIN-LIKE
(Trichormus
variabilis) 		5 / 12 LEU A  14
PHE A  61
LEU A  97
LEU A  95
THR A  75
 None
 1.24A 5ieoA-2nlvA:
undetectable		 5ieoA-2nlvA:
23.48